 This anaesthetic has more than one structural configuration. An example low energy conformer is shown. Surface View:
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Surface view shows the electrostatic potential of the conformer mapped onto
the solvent excluded surface, based on a probe of radius 1.4Å.
Regions of negative potential are shown in red, positive in blue.
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| In Vivo Activity Data | ||
| Immobility: MAC Human (atm) | 0.02 | Bourne JG. Nitrous Oxide in Dentistry. London: Lloyd-Luke, 1960 |
|---|---|---|
| Physical Properties | ||
| Blood / Gas Partition Coeff. at 37°C | 2 | Steward A, Allott PR, Cowles AL & Mapleson WW. Br J Anaesth 1973;45:282-93 |
| Water / Gas Partition Coeff. at 37°C | 1.2 | Steward A, Allott PR, Cowles AL & Mapleson WW. Br J Anaesth 1973;45:282-93 |
| Calculated Molecular Properties | ||
| van der Waals Volume | 57 Å3 | |
| van der Waals Surface Area | 89 Å2 | |
| Solvent Accessible Volume | 262 Å3 | (based on a 1.4Å probe) |
| Solvent Accessible Surface Area | 207 Å2 | (based on a 1.4Å probe) |
All values are mean ± SD, except
data labelled with † which are mean ± SEM.
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Database Version: 1.09.9 Last Updated: 21st February 2014
Database Version: 1.09.9 Last Updated: 21st February 2014