![]() This anaesthetic has more than one structural configuration. An example low energy conformer is shown. Surface View:
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Surface view shows the electrostatic potential of the conformer mapped onto
the solvent excluded surface, based on a probe of radius 1.4Å.
Regions of negative potential are shown in red, positive in blue.
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In Vivo Activity Data | ||
Immobility: MAC Rat (atm) | 0.000611 ± 0.000025 (n=21) | Won A, Oh I, Liao M, et al. Anesth Analg 2006;102:1419-26 |
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Physical Properties | ||
Saline / Gas Partition Coeff. at 37°C | 92.7 ± 1.7 (n=4) | Won A, Oh I, Liao M, et al. Anesth Analg 2006;102:1419-26 |
Olive Oil / Gas Partition Coeff. at 37°C | 2050 ± 20 (n=4) | Won A, Oh I, Liao M, et al. Anesth Analg 2006;102:1419-26 |
Calculated Molecular Properties | ||
van der Waals Volume | 113 Å3 | |
van der Waals Surface Area | 173 Å2 | |
Solvent Accessible Volume | 430 Å3 | (based on a 1.4Å probe) |
Solvent Accessible Surface Area | 315 Å2 | (based on a 1.4Å probe) |
All values are mean ± SD, except
data labelled with † which are mean ± SEM.
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Database Version: 1.09.9 Last Updated: 21st February 2014
Database Version: 1.09.9 Last Updated: 21st February 2014