![]() This anaesthetic has a single low-energy conformer. Surface View:
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Surface view shows the electrostatic potential of the structure mapped onto
the solvent excluded surface, based on a probe of radius 1.4Å.
Regions of negative potential are shown in red, positive in blue.
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In Vivo Activity Data | ||
Immobility: MAC Dog (atm) | 0.0011 ± 0.0002 (n=4) | Eger EI II, Koblin DD, Collins PA. Anesth Analg 1981;60:201-3 |
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Physical Properties | ||
Olive Oil / Gas Partition Coeff. at 37°C | 1286 ± 44 | Eger EI II, Koblin DD, Collins PA. Anesth Analg 1981;60:201-3 |
Calculated Molecular Properties | ||
van der Waals Volume | 114 Å3 | |
van der Waals Surface Area | 141 Å2 | |
Solvent Accessible Volume | 391 Å3 | (based on a 1.4Å probe) |
Solvent Accessible Surface Area | 277 Å2 | (based on a 1.4Å probe) |
Notes | ||
98% Compound in trans form |
All values are mean ± SD, except
data labelled with † which are mean ± SEM.
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Database Version: 1.09.9 Last Updated: 21st February 2014
Database Version: 1.09.9 Last Updated: 21st February 2014